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Answer: Ananda Labs is a biotechnology company focused on developing advanced therapies for reversing aging and treating age-related diseases through epigenetic reprogramming technology.
Answer: Epigenetic reprogramming is a process that alters gene expression without changing the underlying DNA sequence. Ananda Labs utilizes this approach to reverse aging at the cellular level while maintaining the identity and functionality of the cells.
Answer: RPER (Rejuvenation-based Placental Epigenetic Reprogramming) is Ananda Labs’ proprietary technology that uses patented placental and embryonic factors to rejuvenate aged cells, reversing their biological age by up to 50%.
Answer: Ananda Labs’ therapies target a range of age-related conditions including wrinkles, skin damage, hair loss, age-related macular degeneration (AMD), and immune system decline.
Answer: The therapy involves isolating a patient’s skin fibroblasts, rejuvenating them using RPER technology, and reinserting them into the skin to restore elasticity and reduce wrinkles.
Answer: Fibroblasts are skin cells responsible for maintaining skin structure by producing collagen, hyaluronic acid and Elastin. As we age, their function declines, leading to wrinkles and skin sagging.
Answer: The goal is to develop therapies that reverse hair loss and restore natural hair color by rejuvenating hair follicle cells using the RPER technology.
Answer: AMD is a condition that causes central vision loss due to the deterioration of the macula, a part of the retina. It primarily affects older adults.
Answer: The therapy aims to treat AMD by rejuvenating retinal cells using RPER technology, potentially restoring vision and preventing blindness.
Answer: The therapy targets the rejuvenation of immune cells, potentially reducing the risk of age-related diseases such as cancer, Alzheimer’s, and Parkinson’s.
Answer: Ananda Labs’ technology is designed to be safer than existing reprogramming methods by avoiding the risks associated with altering DNA and focusing on enhancing gene expression.
Answer: The RPER technology was developed by Prof. Yosef Buganim, a leading expert in stem cells and reprogramming, in partnership with Ananda Labs.
Answer: Ananda Labs is headquartered in New York City, with additional offices in Tel-Aviv, Israel, and planned expansions in Orange County, California.
Answer: The long-term goals include developing affordable, accessible anti-aging therapies that address root causes of age-related diseases and conditions.
Answer: Ananda Labs has developed a unique, patented set of factors that are safer and more effective than other reprogramming technologies, giving them a competitive advantage in the anti-aging field.
Answer: Yes, Ananda Labs is currently raising funds and offers opportunities for accredited investors to participate in their pioneering work, for more information contact us info@ananda-labs.com.
Answer: Ananda Labs is open to partnerships with biotech, lifestyle, and cosmetic companies to enhance research and development in combating degenerative diseases and age-related conditions.
Answer: Epigenetic aging involves changes in the epigenome that reduce a cell’s ability to respond to environmental cues, leading to inappropriate gene expression and age-related decline.
Answer: The potential impact includes significantly extending healthy lifespans, reducing the incidence of age-related diseases, improving appearance, and enhancing the quality of life for older adults and those who are becoming older
Answer: Current projects include skin fibroblast rejuvenation, hair loss reversal, vision restoration for AMD, and immune system rejuvenation.
Answer: Ananda Labs’ technology is designed to avoid the tumorigenic risks associated with Yamanaka factors by using safer, more targeted reprogramming factors.
Answer: The epigenetic clock is a measure of a cell’s age based on changes in the epigenome, which can be reversed through targeted reprogramming.
Answer: Applications include anti-aging therapies, treatment of degenerative diseases, and potentially reversing cellular aging across various organ systems.
Answer: Ananda Labs’ therapies are based on extensive preclinical research and are continuously optimized for safety and effectiveness.
Answer: The vision is to democratize anti-aging medicine, making it affordable and accessible to the broader population, not just the elite.
Answer: Ananda Labs is aiming to develp a topical cream for ongoing skin rejuvenation that patients can use at home as a complement to clinical treatments.
Answer: The placenta plays a key role as a source of potent factors used in the RPER technology to rejuvenate cells.
Answer: Success is measured by the ability to reverse cellular aging, restore function in aging tissues, and ultimately improve patient outcomes.
Answer: Currently, Ananda Labs is in the research and development stage, with plans to make therapies available following clinical validation and regulatory approval.
Answer: You can learn more by visiting Ananda Labs’ official website,www.ananda-labs.bio,on FaceBook https://www.facebook.com/anandalabsinc,Linkedin https://www.linkedin.com/company/ananda-labs-inc/posts reading our publications, or contacting us directly for specific inquiries.
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Yes.
Answers:
A. Age-related Macular Degeneration (AMD):We plan to inject clinical-grade AAVs encoding the reprogramming factors directly into the eye. The specific AAV serotype has already been calibrated in the lab. We’re collaborating with ophthalmologists at Hadassah hospital who routinely perform this injection technique.
B. Skin:We will take a biopsy from behind the patient’s ear, expand the cells in the lab, and deliver the factors using modified RNAs to control their expression. Our long-term goal is to develop a topical lotion that can deliver the factors directly to the dermis.
C. Immune System: We intend to isolate CD34+ cells from peripheral blood and introduce the factors using clinical-grade AAVs. The serotype for this has also been calibrated in the lab.
Answer: Ten Years of research: Since 2014, the Hebrew University of Jerusalem has studied and developed a unique patented set of factors/genes that can rejuvenate cells, which are believed to be superior to those of our competitors. Prof. Yosef Buganim, a world leader in the field of stem cells and reprogramming, was the first to discover a combination of genes that can convert adult cells into placental stem cells. Given that the chronological age of the placenta is zero (embryonic stage), Prof. Buganim’s method can also rejuvenate cells through site-specific alteration of epigenetic marks.
His research demonstrated that this combination of factors is particularly potent in targeting the genome of adult cells, achieving up to 50% age reversal in adult skin cells while preserving their identity. This age reversal was associated with improved function and healthier cells. Moreover, unlike Yamanaka factors, which carry a tumorigenic risk (formation of teratoma, a benign tumor), Prof. Buganim’s combination is safer.
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